華岡紡織期刊 Journal of the Hwa Gang Textile
ISSN
1025-9678
發行 Publisher
中華民國紡織工程學會
Home / Archives / Vol. 25 No. 1 (2018) / Original Research Articles
Original Research Articles · 研究論文

Cytocompatibility of Phosphate chitosan derivatives

鏻鹽化幾丁聚醣衍生物之細胞相容性
  • Hung-Ching Po 柏鴻靖 Department of Materials and Textiles, Oriental Institute of Technology
  • Yu-Ting Liu 劉昱廷 Department of Materials and Textiles, Oriental Institute of Technology
  • Li-Wei Zheng 鄭力瑋 Department of Materials and Textiles, Oriental Institute of Technology
  • Chien-Hsin Chen 陳建興 Department of Materials and Textiles, Oriental Institute of Technology
  • Chi-Hsiung Jou 周啟雄 ✉ Department of Materials and Textiles, Oriental Institute of Technology

Abstract

In this project, four N-quaternary phosphoniun chitosan derivatives (NQPCS) were synthesized by chitosan and four (N-carboxyalkyl) triphenylphosphonium of compounds (CATPPs). The cytocompatibility were evaluated by L929 fibroblast proliferation and cytotoxicity. Our goal is to demonstrate NQPCS can be applied in textiles, cosmetic and biomedical fields.

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摘要

本研究係以幾丁聚醣與分別與4種N-(羧烷基)三苯基溴化鏻化合物(CATPPs)反應而得4種鏻化幾丁聚醣衍生物(NQPCS)。細胞相容性以L929纖維母細胞來評估其細胞成長活性與細胞毒性。期證明本研究所合成之NQPCS能應用於紡織領域、化妝品及生物醫學等用途。

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