Cytocompatibility of Gallic acid grafted polycationic Chitosan derivates

You-Cyuan Syu; Jhan-Ci Tong; Han-Hsiang Yu; Kuan-Wei Li; Chi-Hsiung Jou

Home / Archives / Vol. 23 No. 2 (2016) / Original Research Articles

Original Research Articles · 研究論文

Cytocompatibility of Gallic acid grafted polycationic Chitosan derivates

含沒食子酸之陽離子型幾丁聚醣衍生物細胞相容性研究

You-Cyuan Syu 許祐銓 Department of Materials and Textiles, Oriental Institute of Technology
Jhan-Ci Tong 童兆麒 Department of Materials and Textiles, Oriental Institute of Technology
Han-Hsiang Yu 游翰翔 Department of Materials and Textiles, Oriental Institute of Technology
Kuan-Wei Li 李冠偉 Department of Materials and Textiles, Oriental Institute of Technology
Chi-Hsiung Jou 周啟雄 ✉ Department of Materials and Textiles, Oriental Institute of Technology

Abstract

In this study, chitosan was modified with glycidyl trimethyl ammonium chloride (GTMAC) to produce N-(2-hydroxyl) propyl-3-trimethyl ammonium chitosan chloride (HTCC). Furthermore, HTCC and was modified with gallic acid to produce HTCC-GA. The HTCC-GA was examined by using Fourier transform infrared spectroscopy (FT-IR) to determine the chemical structure. In addition, the cytocompatibility was evaluated by B16F10 skin melanoma proliferation and test.

Keywords

摘要

本研究先以縮水甘油三甲基氯化銨(glycidyl trimethyl ammonium chloride,GTMAC)合成N-(2-羥基)丙基-3-三甲基氯化銨幾丁聚醣(N-(2-hydroxyl) propyl-3-trimethyl ammonium chitosan chloride) (HTCC)。再將沒食子酸(gallic acid)與HTCC進行接枝反應，合成所得之HTCC-GA幾丁聚醣衍生物。反應合成之產物以傅??紅外線光譜儀(FT-IR)分析其結構，細胞相容性以MTT方法評估皮膚黑色素瘤細胞(B16F10)增生情形，另外以黑色素瘤細胞來評估細胞成長性與毒性。

關鍵字

Also in this issue

Full TOC →

To investigate the Impact of mechanical strength of Polyurethane foam with adding Additives
Ju-An Chang, Jia-Horng Lin, Chen-Hung Huang, Yu-Chun Chuang, Ching-Wen Lou
Effect of Corporate Image and Service Quality and Perceived Risk on Intent of Apparel Online Shopping
C. H. Chen, X. Y. Tsai, Y. T. Jian
Study on the Properties of Swelling and Rebound of Wool Fiber After Sodium Hydroxide Treatment
Wen-bin Li, Wei-lin Xu, Guang-ming Cai
Application of Soilless Cultivation Base of Coffee Grounds Recycling
Y. J. Chen, K. W. Yeh, C. P. Chang
A Study of the Strength of Nanosilica/Braided Composite Plates with a Central Hole
K. H. Tsai, C. L. Hwang, Y. C. Chen

Full text 全文

PDF 全文 → Open Access

Issue: Vol. 23 No. 2 (2016)
Section: Original Research Articles
Pages: 101-105
Submitted: 2016-04-16
Published: 2016-04-16
ID: JHGT-16-195
Views: 1
Downloads: 0

引用 How to cite

Syu, Y. C., Tong, J. C., Yu, H. H., Li, K. W., & Jou, C. H. (2016). Cytocompatibility of Gallic acid grafted polycationic Chitosan derivates. Journal of the Hwa Gang Textile, 23(2), 101-105. https://jhgt.org.tw/article/view/180

@article{syu2016_180,
  author  = {Syu, You-Cyuan and Tong, Jhan-Ci and Yu, Han-Hsiang and Li, Kuan-Wei and Jou, Chi-Hsiung},
  title   = {Cytocompatibility of Gallic acid grafted polycationic Chitosan derivates},
  journal = {Journal of the Hwa Gang Textile},
  year    = {2016},
  volume  = {23},
  number  = {2},
  pages   = {101--105},
  issn    = {1025-9678},
  url     = {https://jhgt.org.tw/article/view/180}
}

TY  - JOUR
AU  - Syu, You-Cyuan
AU  - Tong, Jhan-Ci
AU  - Yu, Han-Hsiang
AU  - Li, Kuan-Wei
AU  - Jou, Chi-Hsiung
TI  - Cytocompatibility of Gallic acid grafted polycationic Chitosan derivates
JO  - Journal of the Hwa Gang Textile
T2  - 華岡紡織期刊
VL  - 23
IS  - 2
PY  - 2016
SP  - 101
EP  - 105
KW  - Gallic Acid
KW  - Chitosan Derivates
KW  - Skin Melanoma
KW  - Cytocompatibility
SN  - 1025-9678
UR  - https://jhgt.org.tw/article/view/180
AB  - In this study, chitosan was modified with glycidyl trimethyl ammonium chloride (GTMAC) to produce N-(2-hydroxyl) propyl-3-trimethyl ammonium chitosan chloride (HTCC). Furthermore, HTCC and was modified with gallic acid to produce HTCC-GA. The HTCC-GA was examined by using Fourier transform infrared spectroscopy (FT-IR) to determine the chemical structure. In addition, the cytocompatibility was evaluated by B16F10 skin melanoma proliferation and test.
ER  -

下載 .ris 下載 .bib

分享 Share